11/15/2012
· Brain InjuryFreeman et al. (2005) noted that it was in the mid-'80s when it was first noted that mild traumatic brain injury (MTBI) could result in serious and lasting consequences. Numerous studies with human and animal subjects have demonstrated the evidence of neurocognitive defects and delayed return to work in MTBI patients with postconcussive syndrome.
Traumatic brain injury (TBI) causes several types of damage to the brain that affect the cerebral cortex, subcortical nuclear structures, and their widespread white matter connections (see chapters by Kochanek et al. and Hovda for more details). The resulting cascade of pathological changes disrupts neural functioning at multiple levels, from individual cellular and vascular structures to the larger brain networks they comprise
