Headache disorders are common worldwide and often disabling. Until recently, treatments were borrowed from other branches of neurology and medicine. Monoclonal antibodies targeting calcitonin gene-related peptide (CGRP) ligand and receptor, small molecule CGRP receptor antagonist gepants, serotonin1F agonists, new devices to deliver currently available drugs, and neuromodulation devices have recently been in the forefront of headache treatments that are rather specific for various headache disorders. These novel therapies are changing the field of headache medicine. Herein, we update the latest data available for these therapies.
Adequate debridement, control of infection, off-loading of pressure, and appropriate topical management are the most important interventions in treating nonhealing wounds.
Protocols for producing experimental heart failure by rapid ventricular pacing are well established ; however, for safety reasons, commonly used clinical pacemakers do not allow pacing rates that are sufficient to induce either heart failure (HF) or atrial fibrillation (AF).
In a remote village in Central America, an otherwise unmanaged child's infection can take a turn for worse if not for the long distance diagnosis capacity brought about by the recently installed telemedicine system between Zacapa, Guatemala, and Houston, Texas, where subspecialists in the field of Pediatric Dermatology viewed the wound and prescribed the critically needed treatment.
Acetaminophen is an analgesic (pain reliever) and anti-pyretic (controls fever) medication that is sold over-the-counter — without a prescription. More than 200 pain relievers and cold remedies under various trade names, including Tylenol, contain acetaminophen.
After 60 years of availability of antibiotics, surprisingly little is known about their role in obstructive airway diseases. Areview of antibiotic therapy will necessarily involve a discussion of the role of bacterial infection in asthma and chronic obstructive pulmonary disease