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Featured Toxicology articles by expert witnesses and consultants. Contact Us if you are interested in having your work published on our website and linked to your Profile(s).

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1/17/2018· Toxicology

Presumptive Testing

By: Dr. Jerald L. Cook

Presumptive tests, also known as preliminary tests or field tests, allow drugs to be quickly classified into a particular chemical group, but do not unequivocally identify the presence of a specific chemical compound. Preliminary drug test results are often included in a panel of tests, which then be used as a guide to an appropriate confirmatory test to determine and verify the chemical compounds present.

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3/3/2011· Toxicology

Possible Contribution Of Indomethacin To The Carcinogenicity Of Nongenotoxic Bladder Carcinogens That Cause Bladder Calculi

By: Harry Milman

Nongenotoxic bladder carcinogens that form bladder calculi have been concluded to be of low carcinogenic risk to humans because bladder stones would be expelled or surgically removed before they had a chance to exert their carcinogenic effect.

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3/19/2018· Toxicology

Cocaine: Acute Toxicity and Presumptive Testing

By: Dr. Jerald L. Cook

Cocaine remains a popular drug of abuse, and per HHS (2008) of 6.5 million US Federal workplace drug tests, about 40,000 were positive for cocaine in 2007. Drug testing for cocaine is based on the metabolite benzoylecogonine which is detectable in the user’s urine for 24 hours, possibly even up to 72 hours. Non-metabolized cocaine may only be detectable for 4-6 hours following use, making it a less useful target in a drug testing program.

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10/2/2018· Sexual Abuse - Molestation - Harassment

The Influence of Psychotic Illness on Victim Credibility in Allegations of Child Sexual Abuse

By: Dr. Mark McDonald

In the absence of physical evidence or eyewitness testimony, establishing a criminal charge of child sexual abuse often boils down to a “he said, she said” weighing of credibility of the accuser and accused. As the burden of proof lies on the prosecution to establish the charge beyond a reasonable doubt, witness testimony becomes paramount in determining the outcome of the case. If the alleged victim is suffering from a serious mental illness, such as psychosis, that impairs one’s ability to either accurately recall the alleged abuse or distinguish reality from fantasy, witness credibility will suffer, and the defendant will likely be found not guilty. For both plaintiff and defense counsel, when there is any suspicion of psychotic illness in the accuser, it is critical to assess the following before trial: type and severity of mental illness, genetics, drug use, previous abuse, and neglect.

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10/3/2018· Toxicology

Genetic Influences in Toxicology: Smoking Might Be Worse For Some Than Others

By: Dr. Jerald Cook

Pharmacogenomics is a field that studies genetic differences in sensitivity to therapeutically used drugs. We have learned that some medications are not effective in some individuals, or super effective and even likely to result in adverse effects in others due to genetic polymorphisms. Similarly, toxicogenomics investigates sensitivities with toxic chemicals, including carcinogens.

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The Practice of Forensic Human...

by Melvin H. Rudov, PhD, H. Harvey Cohen, PhD CPE

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