Neuropharmacology Expert Witnesses: 3

Merrill S. Wise, MD, is Board-Certified in Psychiatry and Neurology with special qualifications in Child Neurology, and he is certified by the American Board of Sleep Medicine. Involved in the full-time practice of sleep medicine, Dr. Wise has evaluated and managed the full range of Sleep Disorders since 1991.

Dr. Wise evaluates children, adolescents, and adults with the full range of sleep problems and disorders. He is involved with supervision and interpretation of polysomnography (sleep studies), Multiple Sleep Latency Tests (MSLT), Maintenance of Wakefulness Tests (MWT), and integration of these findings with the clinical history in order to develop a diagnosis and treatment plan.

Because of the population served in Memphis, Dr. Wise evaluates a large number of pilots (FedEx world hub), air traffic controllers, commercial drivers and barge pilots, rail engineers, and shift workers. He is experienced in the treatment of obstructive sleep apnea (OSA), narcolepsy, and other disorders of excessive sleepiness, insomnia, circadian rhythm sleep disorders, restless legs syndrome, and parasomnias.  This expertise and experience allows him to analyse and provide valuable opinions on a wide range of sleep-related legal issues.

Litigation Support - Dr. Wise has reviewed a wide variety of cases involving both neurology and sleep medicine for greater than 20 years including report generation, testimony at deposition, and at trial. He has served on numerous national task forces and committees, as well as the Board of Directors of the American Academy of Sleep Medicine (AASM). These experiences have exposed him to the full range of sleep disorders, as well as healthcare systems, best practices and evidence-based standards of care, policies, and the legal aspects of sleep problems and disorders. 

Special Interest and Expertise:  

• Individuals with Excessive Daytime Sleepiness
• Downstream Effects of Sleepiness on
  • Cognitive Function
  • Driving
  • Safety
  • Work
  • Behavioral Regulation

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Dr. Nicholas Ladikos is a Clinical Pharmacist and Drug Regimen Error expert. He started and operationalized system-level programs at the Johns Hopkins Hospital and the National Institutes of Health (NIH), and is also the founder of MedOp Advisors, a concierge medication, nutrition, and health & wellness advisory company.

Dr. Ladikos also serves as a Medical Director for Optum Serve and is a Professor at both Texas Tech University and Arizona College of Nursing. He co-authored numerous papers in the areas of infectious diseases and antimicrobial stewardship, pharmacoeconomics, pharmacogenomics, geriatrics, and therapies in the lung transplant population. He conducts physician training and clinical staff education regarding medication trends and utilization, identification and mitigation for potential medication fraud, waste and abuse, and collaborates in disease management and population health programs.

Litigation Support - Dr. Ladikos is a subject matter expert in several pharmacy-related areas and serves as an expert witness on a number of Pharmaceutical litigation matters. Numerous hospitals have used his skillset and expertise in medical chart reviews to identify errors in medication preparation and prescribing, drug side effect management, standard of care compliance, continuing education delivery, and personnel assessments.

Areas of Expertise:

Dr. Ladikos currently develops and leads clinical programs that help stakeholders use and advance medication management tools (e.g., formularies, pharmacy, therapeutics committees and medication therapy management), quality metrics, research methodologies, and health information technology. He has experience in medication utilization statistical analyses to demonstrate adherence to evidence-based practice guidelines and inform health program policies.

Dr. Ladikos examines pharmacoeconomic trends to ensure that a cost-effective pharmacy benefit is administered to members, and consults with care management team to provide guidance regarding member goals.